Ciliary beat frequency of biopsy samples taken from normal persons and patients with various lung diseases

Ciliary beat frequency from human tracheobronchial mucosa was measured in vitro. Biopsy samples were taken during bronchoscopy and beat frequency measured with a phase contrast microscope and a photosensitive cell. In 20 healthy volunteers the mean ciliary beat frequency in the trachea was 12.5 +/-...

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Bibliographic Details
Published inChest Vol. 80; no. 6 Suppl; p. 855
Main Authors Konietzko, N, Nakhosteen, J A, Mizera, W, Kasparek, R, Hesse, H
Format Journal Article
LanguageEnglish
Published United States 01.12.1981
Subjects
Adult
Biopsy
Bronchi - physiology
Bronchial Diseases - physiopathology
Cilia - physiology
Humans
In Vitro Techniques
Lung Diseases - pathology
Lung Diseases - physiopathology
Movement
Trachea - cytology
Trachea - pathology
Trachea - physiology
Trachea - physiopathology
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Summary:Ciliary beat frequency from human tracheobronchial mucosa was measured in vitro. Biopsy samples were taken during bronchoscopy and beat frequency measured with a phase contrast microscope and a photosensitive cell. In 20 healthy volunteers the mean ciliary beat frequency in the trachea was 12.5 +/- 2.8 Hz at 37 degrees C with a wide interindividual range (4.9 to 17.4 Hz), but a good intraindividual reproducibility (+/- 7 percent). There was a slight increase in frequency down the tracheobronchial tree and a decrease at lower temperatures. With some exceptions, no disease-specific correlation in beat frequency seems to exist in different bacterial and malignant bronchopulmonary conditions. However the quantity and quality of ciliated cells brushed from the mucosa does appear to be disease-related.
ISSN:0012-3692
DOI:10.1378/chest.80.6.855