Hemochromatosis, iron, and blood donation: a short review
Hereditary hemochromatosis (HH), an autosomal recessive disease of iron overload, is one of the most common inherited diseases. The candidate gene (HFE) for HH has been identified recently and a DNA-based test for the mutation is available. Treatment for HH patients with elevated iron stores include...
Saved in:
| Published in | Immunohematology Vol. 15; no. 3; p. 108 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
United States
01.01.1999
|
| Online Access | Get more information |
Cover
Loading…
| Summary: | Hereditary hemochromatosis (HH), an autosomal recessive disease of iron overload, is one of the most common inherited diseases. The candidate gene (HFE) for HH has been identified recently and a DNA-based test for the mutation is available. Treatment for HH patients with elevated iron stores include repeated phlebotomy. Left untreated, iron overload can lead to cirrhosis, organ failure, and a shortened life expectancy. In the past and present, blood collected for therapeutic purposes from patients with HH has been discarded. The aim of this article is to address whether blood collected from HH patients should be used for allogeneic transfusion in the future. |
|---|---|
| ISSN: | 0894-203X |
| DOI: | 10.21307/immunohematology-2019-628 |