Evaluation of Lipid Peroxidation—Antioxidant Defense System Depending on the Stage of Stress Reaction in Hypertensive ISIAH Rats

The stages of stress reaction (anxiety and resistance) were reproduced on the model of stresssensitive hypertensive ISIAH rats. Analysis of the experimental data showed an increase in activity of the antioxidant defense system in ISIAH rats: total antioxidant activity of the blood and superoxide dis...

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Published inBulletin of experimental biology and medicine Vol. 166; no. 5; pp. 610 - 612
Main Authors Kolesnikova, L. I., Kolesnikova, L. R., Darenskaya, M. A., Natyaganova, L. V., Grebenkina, L. A., Korytov, L. I., Kolesnikov, S. I.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.03.2019
Springer Nature B.V
Subjects
Antioxidants
Anxiety
Biomedical and Life Sciences
Biomedicine
Cell Biology
Hypertension
Internal Medicine
Laboratory Medicine
Lipid peroxidation
Oxidative stress
Pathology
Superoxide dismutase
arterial hypertension
oxidative stress
stress reaction
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Summary:The stages of stress reaction (anxiety and resistance) were reproduced on the model of stresssensitive hypertensive ISIAH rats. Analysis of the experimental data showed an increase in activity of the antioxidant defense system in ISIAH rats: total antioxidant activity of the blood and superoxide dismutase activity increased at the stage of anxiety and then decreased during the resistance stage.
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ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-019-04402-6