Clinicopathological characterization of mouse models of melanoma

Mouse models of melanoma have proven invaluable in the delineation of key molecular events involved in disease progression in humans and provide potential preclinical models for therapeutic testing (Damsky and Bosenberg, Pigment Cell Melanoma Res 25(4):404-405, 2012; Walker et al., Pigment Cell Mela...

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Bibliographic Details
Published inMethods in molecular biology (Clifton, N.J.) Vol. 1267; p. 251
Main Authors Ferguson, Blake, Soyer, H Peter, Walker, Graeme J
Format Journal Article
LanguageEnglish
Published United States 2015
Subjects
Animals
Dermoscopy
Disease Models, Animal
Eosine Yellowish-(YS) - metabolism
Hematoxylin - metabolism
Immunohistochemistry
Melanocytes - pathology
Melanocytes - radiation effects
Melanoma - diagnosis
Melanoma - etiology
Melanoma - metabolism
Melanoma - pathology
Membrane Glycoproteins - metabolism
Mice
Oxidoreductases - metabolism
Paraffin Embedding
Skin Neoplasms - diagnosis
Skin Neoplasms - etiology
Skin Neoplasms - metabolism
Skin Neoplasms - pathology
SOXE Transcription Factors - metabolism
Staining and Labeling
Tissue Fixation
Ultraviolet Rays - adverse effects
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Summary:Mouse models of melanoma have proven invaluable in the delineation of key molecular events involved in disease progression in humans and provide potential preclinical models for therapeutic testing (Damsky and Bosenberg, Pigment Cell Melanoma Res 25(4):404-405, 2012; Walker et al., Pigment Cell Melanoma Res 24(6):1158-1176, 2011). Here we concentrate on the clinicopathological analysis of melanocytic tumors.
ISSN:1940-6029
DOI:10.1007/978-1-4939-2297-0_11