Synthesis, Characterization and Biological Potency of Butyl‐Pyridone Based Azo Dyes

A series of heterocyclic disperse azo dyes having pyridone architecture was prepared by a simple, economical and highly efficient diazo‐coupling method. In this method, butyl pyridone was used as a common coupling component by changing the five heterocyclic amine moieties. The structural investigati...

Full description

Saved in:
Bibliographic Details
Published inChemistrySelect (Weinheim) Vol. 5; no. 18; pp. 5460 - 5464
Main Authors Kumar, Vinod, Keshavayya, J., Matada, Mallikarjuna N., Srinivasa, Sudhanva M., Rangappa, S.
Format Journal Article
LanguageEnglish
Published 14.05.2020
Subjects
Azo compounds
Biological activity
Butyl pyridone
Diazotization
Online AccessGet full text

Cover

More Information
Summary:A series of heterocyclic disperse azo dyes having pyridone architecture was prepared by a simple, economical and highly efficient diazo‐coupling method. In this method, butyl pyridone was used as a common coupling component by changing the five heterocyclic amine moieties. The structural investigations of the analogous compounds were accomplished by various spectroscopic techniques. Further, all the azo dyes were examined for their potency towards antibacterial, antituberculosis and anticancer activities. The results revealed that all the dye molecules exhibited excellent tuberculosis activity and also very promising anticancer activity. In the case of the antibacterial assay, only a few azo dyes displayed good inhibition effect towards the tested bacterial strains. The five different azo colourants were prepared via diazotization method by using butyl pyridone as a common coupling compound at 0–5 °C as per the scheme given in graphical . The synthesized compounds were screened for different biological activities to know their biological efficacy.
ISSN:2365-6549
2365-6549
DOI:10.1002/slct.201904954