A “Clickable” Electrodeposited Polymer Films Based on 3‐Ethynylthiophene for the Covalent Immobilization of Proteins. Application to a Label‐free Electrochemical Immunosensor for Escherichia Coli and Staphylococcus Aureus Determination

• Published in: Electroanalysis (New York, N.Y.) Vol. 33; no. 12; pp. 2469 - 2475
• Main Authors: Svalova, T. S., Medvedeva, M. V., Kozitsina, A. N.
• Format: Journal Article
• Language: English
• Published: 01.12.2021
• Subjects: 3,4-ethylendioxythiophene; 3-ethynylthiophene; copper catalysed azide-alkyne cycloaddition; covalent immobilization of proteins; Electrochemical polymerization; label-free electrochemical immunosensor; layer-by-layer electrodeposition

An original electrodeposited polymer film, based on 3‐ethynylthiophene, for covalent immobilization of proteins via “click” reaction of copper catalyzed azide‐alkyne cycloaddition was developed. The best characteristics have demonstrated the layer‐by‐layer immobilized 3,4‐ethylendioxythiophene‐3‐eth...