Reactivity of sera collected from dogs in Mutare, Zimbabwe, to antigens of Ehrlichia canis and Cowdria ruminantium

Six of 20 sera from apparently healthy dogs in Mutare, Zimbabwe, contained antibodies which were reactive with Cowdria ruminantium and Ehrlichia canis in indirect fluorescent antibody tests at similar titres. In Western blots these sera recognised the immunodominant antigen bands of the two organism...

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Bibliographic Details
Published inVeterinary record Vol. 134; no. 19; p. 498
Main Authors Matthewman, L A, Kelly, P J, Mahan, S M, Semu, S M, Mason, P R, Bruce, D, Brouqui, P, Raoult, D
Format Journal Article
LanguageEnglish
Published England 07.05.1994
Subjects
Animals
Antibodies, Bacterial - immunology
Antigens, Bacterial - immunology
Cross Reactions
Dog Diseases - immunology
Dogs - immunology
Ehrlichiosis - immunology
Ehrlichiosis - veterinary
Heartwater Disease - immunology
Immunodominant Epitopes - immunology
Zimbabwe
Zimbabwe
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Summary:Six of 20 sera from apparently healthy dogs in Mutare, Zimbabwe, contained antibodies which were reactive with Cowdria ruminantium and Ehrlichia canis in indirect fluorescent antibody tests at similar titres. In Western blots these sera recognised the immunodominant antigen bands of the two organisms. Sera with high titres (> 1/80) recognised additional antigen bands of each organism. It was not possible to determine whether these dogs had been exposed to C ruminantium, E canis or other Ehrlichia species. In areas where these organisms coexist serological tests for canine ehrlichiosis should be interpreted with caution.
ISSN:0042-4900
DOI:10.1136/vr.134.19.498