Synthesis and structure of novel 6-(pyrazol-1-yl)-4-methyl-1H-pyrazolo[3,4-b]pyridin-3-ol derivatives

New 6-(pyrazol-1-yl)pyrazolo[3,4-b]pyridin-3-ol compounds were synthesized by cyclization reaction from 2,6-dichloro-4-methylnicotinonitrile. Their derivatives exist as the 3-hydroxy tautomer. The structure of the compound 1a of one of the resulting compounds was studied in detail by X-ray diffracti...

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Bibliographic Details
Published inResearch on chemical intermediates Vol. 40; no. 1; pp. 239 - 247
Main Authors Wu, Ai Qun, Tang, Yong, Huang, Su-Yu, Shen, Li-Qun
Format Journal Article
LanguageEnglish
Published Dordrecht Springer Netherlands 2014
Subjects
Catalysis
Chemistry
Chemistry and Materials Science
Inorganic Chemistry
Physical Chemistry
X-ray diffraction
3-Hydroxy tautomer
Pyrazol
Pyrazolo[3,4-b]pyridine
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Summary:New 6-(pyrazol-1-yl)pyrazolo[3,4-b]pyridin-3-ol compounds were synthesized by cyclization reaction from 2,6-dichloro-4-methylnicotinonitrile. Their derivatives exist as the 3-hydroxy tautomer. The structure of the compound 1a of one of the resulting compounds was studied in detail by X-ray diffraction.
ISSN:0922-6168
1568-5675
DOI:10.1007/s11164-012-0958-2