Patent foramen ovale closure: past, present and future
Patent foramen ovale (PFO) is a common congenital abnormality that has been implicated in a number of disease processes, including cryptogenic stroke and migraine headaches. Medical treatment for these processes is often considered inadequate and mechanical closure of the PFO is an attractive, albei...
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Published in | Expert review of cardiovascular therapy Vol. 5; no. 5; pp. 881 - 891 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
London
Taylor & Francis
01.09.2007
Informa Healthcare |
Subjects | |
Online Access | Get full text |
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Summary: | Patent foramen ovale (PFO) is a common congenital abnormality that has been implicated in a number of disease processes, including cryptogenic stroke and migraine headaches. Medical treatment for these processes is often considered inadequate and mechanical closure of the PFO is an attractive, albeit controversial, alternative. PFO closure has become common practice in many centers, although recent guidelines limit its indication to certain subsets of patients. This review first focuses on the anatomy, physiology and pathophysiology of PFO, and then reviews the currently available and experimental devices for PFO closure, as well as the present clinical data pertaining to them. Finally, we present our perspective of the PFO closure, with regard to its current use and future directions. |
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ISSN: | 1477-9072 1744-8344 |
DOI: | 10.1586/14779072.5.5.881 |