Making good of a tricky start: How IgE and mast cells manage a protective sway in food allergy

• Published in: Immunity (Cambridge, Mass.) Vol. 56; no. 9; pp. 1988 - 1990
• Main Authors: Miranda-Waldetario, Mariana C.G., Curotto de Lafaille, Maria A.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 12.09.2023
• ISSN: 1074-7613; 1097-4180; 1097-4180
• DOI: 10.1016/j.immuni.2023.08.010

The immune and nervous systems respond to dangerous stimuli to maintain homeostasis. In a recent issue of Nature, Florsheim et al. and Plum et al. uncover the crosstalk between immunoglobulin E (IgE)-mast-cell-mediated immune activation and neural responses driving behavioral avoidance of allergenic food. The immune and nervous systems respond to dangerous stimuli to maintain homeostasis. In a recent issue of Nature, Florsheim et al. and Plum et al. uncover the crosstalk between immunoglobulin E (IgE)-mast-cell-mediated immune activation and neural responses driving behavioral avoidance of allergenic food.