A CORTICOID SYNTHESIS FROM 9-ALPHA-HYDROXYANDROST-4-ENE-3,17-DIONE VIA A STEROIDAL OXAZOLINE
The synthesis of 21-acetoxy-17-alpha-hydroxy-16-beta-methylpregna-1,4,9(11)-triene from 9-alpha-hydroxyandrost-4-ene-3,17-dione via a 17-cyanohydrin and a 17-oxazoline is described.
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Published in | J. Chem. Soc., Perkin Trans. 1 no. 10; pp. 1195 - 1196 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
CAMBRIDGE
Royal Soc Chemistry
1992
Royal Society of Chemistry |
Subjects | |
Online Access | Get full text |
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Summary: | The synthesis of 21-acetoxy-17-alpha-hydroxy-16-beta-methylpregna-1,4,9(11)-triene from 9-alpha-hydroxyandrost-4-ene-3,17-dione via a 17-cyanohydrin and a 17-oxazoline is described. |
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ISSN: | 0300-922X 2050-8255 1364-5463 |
DOI: | 10.1039/p19920001195 |