(5R)-7,8/9,10-DI-O-ISOPROPYLIDENE-2,6-DIOXA-4-AZASPIRO[4,5]DECAN-3-ONE - A NEW CHIRAL SPIROOXAZOLIDIN-2-ONE DERIVED FROM D-(+)-GALACTOSE FOR USE IN ASYMMETRIC TRANSFORMATIONS
Starting from D-(+)-galactose, the crystalline spirooxazolidin-2-one 2 can be readily prepared in an optically pure state by a nitrene-mediated four-step sequence, and serves to control both aldol and Diels-Alder reactions with high chiral efficiency, being easy to remove after use.
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Published in | Journal of the Chemical Society. Chemical communications no. 14; pp. 1146 - 1147 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
CAMBRIDGE
Royal Soc Chemistry
1993
Royal Society of Chemistry |
Subjects | |
Online Access | Get full text |
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Summary: | Starting from D-(+)-galactose, the crystalline spirooxazolidin-2-one 2 can be readily prepared in an optically pure state by a nitrene-mediated four-step sequence, and serves to control both aldol and Diels-Alder reactions with high chiral efficiency, being easy to remove after use. |
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ISSN: | 0022-4936 |
DOI: | 10.1039/c39930001146 |