Homologous blood syndrome in dogs. Effect of erythrocyte and platelet antibodies

Isovolemic perfusion of 50% of the recipient circulating blood volume was carried out in intact mongrel dogs using whole donor blood as well as plasma or platelet suspensions in saline. Perfusion against the background of circulating red blood cells (RBC) or platelets antibodies in the donor or in t...

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Bibliographic Details
Published inEuropean surgical research Vol. 11; no. 2; p. 127
Main Authors Belotsky, S M, Portnoy, V F, Matchulin, A V, Dvortsin, G F
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1979
Subjects
Animals
Antibodies
Blood Group Incompatibility
Blood Platelets - immunology
Dogs
Erythrocytes - immunology
Hemodynamics
Transplantation, Homologous
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Summary:Isovolemic perfusion of 50% of the recipient circulating blood volume was carried out in intact mongrel dogs using whole donor blood as well as plasma or platelet suspensions in saline. Perfusion against the background of circulating red blood cells (RBC) or platelets antibodies in the donor or in the recipient was followed by severe and sometimes fatal homologous blood syndrome in a majority of the dogs. Weak and short-term reactions were seen in a few dogs if red blood cells and platelet antibodies were absent.
ISSN:0014-312X
DOI:10.1159/000128059