A clinical evaluation of a card agglutination test for rheumatoid factor

The Macro-Vue Card Test for Rheumatoid Factor (Hynson, Westcott, and Dunning) is a new commercially available card agglutination test designed for qualitative and quantitative procedures. Coded sera from 195 patients, six known positive sera, and two positive serum pools were tested using four comme...

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Bibliographic Details
Published inAmerican journal of clinical pathology Vol. 73; no. 1; pp. 110 - 113
Main Authors Hansen, S L, Mazer, F D, Klinefelter, H F
Format Journal Article
LanguageEnglish
Published England 01.01.1980
Subjects
Arthritis, Rheumatoid - blood
False Negative Reactions
False Positive Reactions
Hemagglutination Tests - methods
Humans
Reference Standards
Rheumatoid Factor - analysis
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Summary:The Macro-Vue Card Test for Rheumatoid Factor (Hynson, Westcott, and Dunning) is a new commercially available card agglutination test designed for qualitative and quantitative procedures. Coded sera from 195 patients, six known positive sera, and two positive serum pools were tested using four commercial kits. The commercial kits evaluated included latex (Hyland RA Test, Behring-Rapi/tex RF Test), sheep erythrocytes (Wampole, Rheumaton), and charcoal (HWD-Macro-Vue RF Card Test) as carrier particles. Using the prescribed quantitative procedures, the percentages of positive and negative results for rheumatoid factor detected by each product were determined after the (serum) code was broken. The Macro-Vue test compares well with the Behring and Hyland latex dilution systems, and appears to detect more positive sera than the Wampole test. Titers obtained using the Macro-Vue test were more reproducible day to day with known positive sera than were titers obtained using any of the other kits.
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ISSN:0002-9173
1943-7722
DOI:10.1093/ajcp/73.1.110