Synthesis and Crystal Structures of 4-Chloro-N′-(4-hydroxy-3-nitrobenzylidene)benzohydrazide monohydrate and 4-Chloro-N′-(4-hydroxy-3-methoxybenzylidene)benzohydrazide monohydrate

• Published in: Journal of chemical crystallography Vol. 41; no. 11; pp. 1707 - 1711
• Main Authors: Lei, Yan, Li, Ting-Zhen, Fu, Chuan, Guan, Xiao-Lin, Tan, Yao
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.11.2011
• Subjects: Chemistry; Chemistry and Materials Science; Crystallography and Scattering Methods; Inorganic Chemistry; Organometallic Chemistry; Original Paper; Physical Chemistry; Hydrazone compound; Synthesis; Hydrogen bonding; Crystal structure
• ISSN: 1074-1542; 1572-8854
• DOI: 10.1007/s10870-011-0161-0

Two new hydrazone compounds, 4-chloro- N′ -(4-hydroxy-3-nitrobenzylidene)benzohydrazide monohydrate ( 1 ) and 4-chloro- N′ -(4-hydroxy-3-methoxybenzylidene)benzohydrazide monohydrate ( 2 ), were synthesized and characterized by physico-chemical methods and single crystal X-ray diffraction. Compound 1 crystallizes in the monoclinic space group P 2 1 / c with unit cell parameters a  = 23.257(3) Å, b  = 4.829(1) Å, c  = 12.763(2) Å, β  = 96.017(2)°, V  = 1425.5(5) Å 3 , Z  = 4, R 1  = 0.0525, and wR 2  = 0.1120. Compound 2 crystallizes in the monoclinic space group P 2 1 / c with unit cell parameters a  = 8.103(3) Å, b  = 21.321(3) Å, c  = 10.594(3) Å, β  = 120.281(2)°, V  = 1580.5(8) Å 3 , Z  = 4, R 1  = 0.0480, and wR 2  = 0.1078. Both compounds contains a hydrazone molecule and a water molecule. The crystals of the compounds are stabilized by N–H···O, O–H···O, and O–H···N hydrogen bonds. Graphical Abstract Two new hydrazone compounds have been synthesized and characterized by physico-chemical methods and single crystal X-ray diffraction.