Prolonged bleeding time in children and young adults with hemophilia

Of 49 patients with hemophilia A or B, who had not received replacement transfusions for at least 72 hours, ten were demonstrated to have a prolonged value for the bleeding time. None had evidence of von Willebrand's disease or prior aspirin ingestion, and only one was found to have an associat...

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Bibliographic Details
Published inPediatrics (Evanston) Vol. 66; no. 6; p. 951
Main Authors Buchanan, G R, Holtkamp, C A
Format Journal Article
LanguageEnglish
Published United States 01.12.1980
Subjects
Adolescent
Adult
Aspirin - pharmacology
Bleeding Time
Blood Platelets - drug effects
Child
Child, Preschool
Hemophilia A - blood
Hemophilia B - blood
Hemostasis
Humans
Infant
Platelet Aggregation
Platelet Function Tests
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Summary:Of 49 patients with hemophilia A or B, who had not received replacement transfusions for at least 72 hours, ten were demonstrated to have a prolonged value for the bleeding time. None had evidence of von Willebrand's disease or prior aspirin ingestion, and only one was found to have an associated intrinsic platelet defect. It appears that the bleeding time, generally thought to be a measurement of platelet-subendothelium interaction, may also sometimes be prolonged in congenital coagulation disorders in which platelet function is normal.
ISSN:0031-4005
DOI:10.1542/peds.66.6.951