Palladium-catalyzed direct phosphonation of azoles with dialkyl phosphites
The first Pd-catalyzed direct phosphonation of azoles with dialkyl phosphites has been achieved without addition of base or acid. This method involves the oxidative cleavage of C-H and P(O)-H bonds and represents an atom-efficiency alternative to the classical phosphonation of Ar-X. A Pd-II/Pd-IV me...
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Published in | Chemical communications (Cambridge, England) Vol. 48; no. 42; pp. 5181 - 5183 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
CAMBRIDGE
Royal Soc Chemistry
25.05.2012
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Subjects | |
Online Access | Get full text |
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Summary: | The first Pd-catalyzed direct phosphonation of azoles with dialkyl phosphites has been achieved without addition of base or acid. This method involves the oxidative cleavage of C-H and P(O)-H bonds and represents an atom-efficiency alternative to the classical phosphonation of Ar-X. A Pd-II/Pd-IV mechanism has been studied and proposed. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1359-7345 1364-548X |
DOI: | 10.1039/c2cc30429e |