A highly sensitive and reductant-resistant fluorescent probe for nitroxyl in aqueous solution and serum

A novel coumarin-based fluorescent probe, P-CM, for quantitative detection of nitroxyl (HNO) was developed. P-CM exhibits a selective response to HNO over other biological reductants and was also applied for quantitative detection of HNO in bovine serum with satisfactory results.

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 50; no. 43; pp. 5790 - 5792
Main Authors Mao, Guo-Jiang, Zhang, Xiao-Bing, Shi, Xue-Lin, Liu, Hong-Wen, Wu, Yong-Xiang, Zhou, Li-Yi, Tan, Weihong, Yu, Ru-Qin
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 01.06.2014
Subjects
Animals
Cattle
Chemistry
Chemistry, Multidisciplinary
Fluorescent Dyes - chemistry
Nitrogen Oxides - blood
Nitrogen Oxides - chemistry
Physical Sciences
Reducing Agents - chemistry
Science & Technology
Spectrometry, Fluorescence
Water - chemistry
QUANTITATIVE DETECTION
ANION
DISCRIMINATION
GLUTATHIONE
ENHANCEMENT
NITRIC-OXIDE
HNO
CHEMISTRY
MECHANISMS
ANGELIS SALT
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Summary:A novel coumarin-based fluorescent probe, P-CM, for quantitative detection of nitroxyl (HNO) was developed. P-CM exhibits a selective response to HNO over other biological reductants and was also applied for quantitative detection of HNO in bovine serum with satisfactory results.
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SourceType-Scholarly Journals-1
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ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc01440e