Primary Isoniazid Mono-Resistant Extrapulmonary Tuberculosis Presenting as Cervical Lymphadenitis: The World’s First Case of Its Type

Tuberculosis is commonly seen in endemic countries. Cases of primary drug resistance are rare. There is a paucity of data related to primary drug resistance at extrapulmonary sites. Herein, a case of primary isoniazid mono-resistant extrapulmonary tuberculosis of the multiple right cervical lymph no...

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Bibliographic Details
Published inCurēus (Palo Alto, CA) Vol. 15; no. 7
Main Author Yadav, Sankalp
Format Journal Article
LanguageEnglish
Published Palo Alto Cureus Inc 15.07.2023
Cureus
Subjects
Acids
Chemotherapy
Drug resistance
Epidemiology/Public Health
Fatalities
Hepatitis
Infections
Infectious Disease
Internal Medicine
Lungs
Lymphatic system
Multidrug resistant organisms
Public health
Tuberculosis
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Summary:Tuberculosis is commonly seen in endemic countries. Cases of primary drug resistance are rare. There is a paucity of data related to primary drug resistance at extrapulmonary sites. Herein, a case of primary isoniazid mono-resistant extrapulmonary tuberculosis of the multiple right cervical lymph nodes is presented. This patient reported multiple swellings and discharging sinuses. A battery of investigations with an eye for finding drug resistance led to a definite diagnosis. He was initiated on an anti-tubercular regimen per the national guidelines. A detailed literature search revealed that no such case of primary isoniazid mono-resistant extrapulmonary tuberculosis presenting as cervical lymphadenitis has ever been reported.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.41937