Effects of specimen evaporation on quality control

Serum samples stored in a refrigerator and in ambient room air were studied for alteration of mean weight and mean concentration values. The storage period selected was four hours and the samples were variously stored exposed, refrigerated, and covered with a sample tray cover and by an airtight cov...

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Bibliographic Details
Published inAmerican journal of clinical pathology Vol. 66; no. 4; pp. 645 - 652
Main Authors Glenn, G C, Hathaway, T K
Format Journal Article
LanguageEnglish
Published England 01.10.1976
Subjects
Air
Blood Preservation - standards
Blood Specimen Collection - standards
Humans
Quality Control
Temperature
Time Factors
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Summary:Serum samples stored in a refrigerator and in ambient room air were studied for alteration of mean weight and mean concentration values. The storage period selected was four hours and the samples were variously stored exposed, refrigerated, and covered with a sample tray cover and by an airtight cover. Some storage procedures produced values more than 2 SD from the mean for many analytes. These findings were confirmed by a parallel study revealing a decrease of sample weight after the four-hour storage period. Storage at 4 C in sample cups covered by an airtight opaque shield alleviated the problem. Failure to treat external quality control sample pools in the same way as other samples will produce unexplained out-of-control results.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0002-9173
1943-7722
DOI:10.1093/ajcp/66.4.645