Infantile hypercalcemia with subcutaneous fat necrosis. Report of a case with studies on the pathogenesis of hypercalcemia

A case of hypercalcemia in neonatal subcutaneous fat necrosis, which was successfully treated with a low Ca and vitamin D-free formula, is described. Low 1,25(OH)2D and severe calciuria, which were considered to result from hypercalcemia itself as well as parathyroid suppression, were noted during t...

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Bibliographic Details
Published inActa pædiatrica Scandinavica Vol. 75; no. 6; p. 1042
Main Authors Yasuda, T, Sunami, S, Ogura, N, Nishioka, T, Nakajima, H
Format Journal Article
LanguageEnglish
Published Sweden 01.11.1986
Subjects
Cerebral Infarction - diagnostic imaging
Cerebral Infarction - etiology
Fat Necrosis - complications
Female
Humans
Hypercalcemia - etiology
Infant
Infant, Newborn
Necrosis - complications
Tomography, X-Ray Computed
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Summary:A case of hypercalcemia in neonatal subcutaneous fat necrosis, which was successfully treated with a low Ca and vitamin D-free formula, is described. Low 1,25(OH)2D and severe calciuria, which were considered to result from hypercalcemia itself as well as parathyroid suppression, were noted during the hypercalcemic phase. The oral Ca load test was repeatedly normal, suggesting that intestinal hyperabsorption of Ca was not a cause of the hypercalcemia. Later recurrence of calciuria without hypercalcemia was noted concomitant with softening of indurated calcified necrotic tissue. In this patient, cerebral infarction on the left side was detected by CT scanning.
ISSN:0001-656X
DOI:10.1111/j.1651-2227.1986.tb10340.x