Cholecystopleural fistula: A case report and literature review

• Published in: Medicine (Baltimore) Vol. 103; no. 33; p. e39366
• Main Authors: Yang, Yong, Chen, Qian, Hu, Yi, Zhao, Liangsong, Cai, Pengcheng, Guo, Suqi
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 16.08.2024
• Subjects: Biliary Fistula - diagnosis; Biliary Fistula - etiology; Biliary Fistula - surgery; Cholangiopancreatography, Endoscopic Retrograde; Cholecystitis, Acute - complications; Cholecystitis, Acute - diagnosis; Cholecystitis, Acute - surgery; Clinical Case Report; Drainage - methods; Humans; Male; Middle Aged; Pleural Diseases - diagnosis; Pleural Diseases - etiology; Pleural Effusion - etiology; Pleural Effusion - therapy; Tomography, X-Ray Computed
• ISSN: 1536-5964; 0025-7974; 1536-5964
• DOI: 10.1097/MD.0000000000039366

Gallstone with acute cholecystitis is one of the most common diseases in the clinic. If the disease is serious, gallbladder gangrene, perforation, and sepsis may be caused. Gallbladder diseases rarely cause thoracic-related complications, especially pleural fistula, which is very rare in clinical practice. A 52-year-old male patient was admitted to the emergency department for 1 month with recurrent right middle and upper abdominal pain. Computed tomography diagnosis: cholecystitis and peri-inflammation, small abscess around the base of the gallbladder, local peritonitis, and bilateral pleural effusion. After admission, conservative treatment was given. On the 4th day of admission, the symptoms worsened, and an emergency catheter drainage was performed on the right thoracic cavity to extract 900 mL of dark yellow effusion. After the operation, a large amount of bili-like fluid was continuously drained from the thoracic drainage tube. After the iatrogenic biliary fistula caused by thoracic puncture was excluded, cholecystopleural fistula was considered to be cholecystopleural fistula. On the 6th day of admission, endoscopic retrograde cholangiopancreatography (ERCP) + cholecystography + Oddi sphincterotomy + laminating biliary stent was performed in the emergency department, and cholecystopleural fistula was confirmed during the operation. The patient recovered well after surgery, computed tomography examination on the 20th day after surgery indicated that pleural effusion was significantly reduced, and the patient was cured and discharged. The patient returned to the hospital 8 months after the ERCP operation to pull out the bile duct-covered stent. The patient did not complain of any discomfort after the postoperative follow-up for 3 years, and no recurrence of stones, empyema, and other conditions was found. Cholecystopleural fistula is one of the serious complications of acute cholecystitis, which is easy to misdiagnose clinically. If the gallbladder inflammation is severe, accompanied by pleural effusion, the pleural effusion is bili-like liquid, or the content of bilirubin is abnormally elevated, the existence of the disease should be considered. Once the diagnosis is clear, active surgical intervention is needed to reduce the occurrence of complications. Endoscopic therapy (ERCP) can be used as both a diagnostic method and an important minimally invasive treatment.