Immunophysiology versus immunopathology: Natural autoimmunity in human health and disease

Based on the analysis of literature and our own data, some key concepts of natural autoimmunity are reviewed from the point of the Pathophysiology: immunological regulation of homeodynamics, physiological autoimmunity versus autoallergy and predictive roles of natural autoantibodies are discussed. H...

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Published inPathophysiology (Amsterdam) Vol. 19; no. 3; pp. 221 - 231
Main Authors Poletaev, A.B., Churilov, L.P., Stroev, Yu.I., Agapov, M.M.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ireland Ltd 01.06.2012
Subjects
Apoptosis
Autoallergy
Autoimmune thyroiditis
Cell mosaics
Chimerism
Immunacea
Immunculus
Immunotherapy
Natural autoimmunity
Prediction of diseases
Autoallergy
Immunotherapy
Cell mosaics
Natural autoimmunity
Immunculus
Chimerism
Autoimmune thyroiditis
Immunacea
Prediction of diseases
Apoptosis
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Summary:Based on the analysis of literature and our own data, some key concepts of natural autoimmunity are reviewed from the point of the Pathophysiology: immunological regulation of homeodynamics, physiological autoimmunity versus autoallergy and predictive roles of natural autoantibodies are discussed. Hypothesis of Immunculus and principle of Immunacea are correlated to some of clinical examples with immunopathological data and the perspectives of autoimmunomics are described.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0928-4680
1873-149X
DOI:10.1016/j.pathophys.2012.07.003