Synthesis of 5-Oxo-2,5-Dihydro-3-Furancarboxylates Using Nano-CuO
Nano-CuO has been used as an efficient catalyst for the preparation of 5-oxo-2,5-dihydro-3-furancarboxylates by multi-component reactions of phenylglyoxal, dimethyl acetylenedicarboxylate and primary amines. The best results were obtained in the presence of 2 mol% of nano-CuO in CH 2 Cl 2 at room te...
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Published in | Polycyclic aromatic compounds Vol. 42; no. 9; pp. 6389 - 6397 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Philadelphia
Taylor & Francis
21.10.2022
Taylor & Francis Ltd |
Subjects | |
Online Access | Get full text |
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Summary: | Nano-CuO has been used as an efficient catalyst for the preparation of 5-oxo-2,5-dihydro-3-furancarboxylates by multi-component reactions of phenylglyoxal, dimethyl acetylenedicarboxylate and primary amines. The best results were obtained in the presence of 2 mol% of nano-CuO in CH
2
Cl
2
at room temperature. The structures of the products were deduced from their
1
H NMR,
13
C NMR, FT-IR, and elemental analyses. Experimental simplicity, wide range of products, excellent yields in short reaction times, reusability of the catalyst and low catalyst loading are some of the substantial features of this method. |
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ISSN: | 1040-6638 1563-5333 |
DOI: | 10.1080/10406638.2021.1982732 |