Quantitative structure activity-relationships for toxicity screening of pesticide impurities for regulatory submission - practical experiences and challenges

The toxicological assessment of impurities of the technical active substance in pesticides with quantitative structure activity-relationship modelling has become an important aspect in authorisation by regulatory bodies. This paper discusses the challenges and drawbacks when predicting toxicities of...

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Bibliographic Details
Published inToxicological and environmental chemistry Vol. 99; no. 7-8; pp. 1071 - 1077
Main Authors Pudenz, Stefan, Frère, Asta Ruzgyte
Format Journal Article
LanguageEnglish
Published Abingdon Taylor & Francis 14.09.2017
Taylor & Francis Ltd
Subjects
Agrochemicals
Impurities
Pesticides
QSARs
regulatory submission
Toxicity
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Summary:The toxicological assessment of impurities of the technical active substance in pesticides with quantitative structure activity-relationship modelling has become an important aspect in authorisation by regulatory bodies. This paper discusses the challenges and drawbacks when predicting toxicities of impurities of technical active substances of pesticides for regulatory submission.
ISSN:0277-2248
1029-0486
DOI:10.1080/02772248.2016.1265649