Fructose-sorbitol malabsorption

Important dietary carbohydrates such as fructose and sorbitol are incompletely absorbed in the normal small intestine. This malabsorption is sometimes associated with abdominal complaints and diarrhea development, symptoms indistinguishable from those of functional bowel disease. Recently, polymeriz...

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Bibliographic Details
Published inCurrent gastroenterology reports Vol. 11; no. 5; pp. 368 - 374
Main Authors Fernández-Bañares, Fernando, Esteve, Maria, Viver, Josep M.
Format Journal Article
LanguageEnglish
Published New York Current Science Inc 01.10.2009
Springer Nature B.V
Subjects
Breath Tests
Evidence-Based Medicine
Fructose - metabolism
Fructose Intolerance - metabolism
Gastroenterology
Humans
Intestinal Absorption
Irritable Bowel Syndrome - metabolism
Irritable Bowel Syndrome - prevention & control
Malabsorption Syndromes - metabolism
Medicine
Medicine & Public Health
Sorbitol - metabolism
Sweetening Agents - metabolism
Sorbitol
Irritable Bowel Syndrome Patient
Fructan
Irritable Bowel Syndrome
Fructose
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Summary:Important dietary carbohydrates such as fructose and sorbitol are incompletely absorbed in the normal small intestine. This malabsorption is sometimes associated with abdominal complaints and diarrhea development, symptoms indistinguishable from those of functional bowel disease. Recently, polymerized forms of fructose (fructans) also were implicated in symptom production in patients with irritable bowel syndrome (IBS). Evidence from uncontrolled and controlled challenge studies suggests that malabsorbed sugars (fructose, sorbitol, lactose) and fructans may act as dietary triggers for clinical symptoms suggestive of IBS. Further placebo-controlled studies are needed to obtain definite conclusions about the role of dietary sugar malabsorption in functional bowel disease.
ISSN:1522-8037
1534-312X
DOI:10.1007/s11894-009-0056-9