SERODIAGNOSIS OF DENGUE VIRUS INFECTION IN PATIENTS PRESENTING TO A TERTIARY CARE HOSPITAL

• Published in: Indian journal of medical microbiology Vol. 24; no. 4; pp. 280 - 282
• Main Authors: Neeraja, M, Lakshmi, V, Teja, VD, Umabala, P, Subbalakshmi, MV
• Format: Journal Article
• Language: English
• Published: India Elsevier B.V 01.10.2006
• Subjects: Academic Medical Centers; Adolescent; Adult; Aged; Antibodies, Viral - blood; Arthropoda; Child; Dengue - diagnosis; Dengue - mortality; Dengue - physiopathology; Dengue - virology; Dengue haemorrhagic fever; dengue shock syndrome; Dengue virus; Dengue Virus - immunology; Female; Humans; IgG; IgM; Immunoglobulin G - blood; Immunoglobulin M - blood; India - epidemiology; Male; Middle Aged; primary infection; secondary infection; Serologic Tests; Severe Dengue - diagnosis; Severe Dengue - mortality; Severe Dengue - physiopathology; Severe Dengue - virology; Shock, Septic - diagnosis; Shock, Septic - mortality; Shock, Septic - virology; India; IgG; primary infection; dengue shock syndrome; Dengue haemorrhagic fever; secondary infection; IgM
• ISSN: 0255-0857
• DOI: 10.1016/S0255-0857(21)02289-1

Dengue is an acute infectious disease of viral etiology. It is probably one of the most important arthropod borne viral disease in terms of human morbidity and mortality. The spectrum of disease ranges from self-limited dengue fever to more severe forms of dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Laboratory diagnosis of dengue virus infection mainly depends on detection of virus specific antibodies. The aim of the study was to correlate the serological results with clinical presentation in patients with a diagnosis of dengue. Eleven out of 15 (73.3%) patients with DHF and DSS had secondary antibody response and mortality was 100% in these patients.