Anaphylactic shock associated with chymopapain skin test. A case report and review of the literature

The allergic response to chymopapain intradiscal therapy has been well documented. The most serious of these reactions is anaphylactic shock, which may result in death. Various screening methods, including skin tests, have been proposed to identify susceptible patients. Anaphylactic shock occurred i...

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Bibliographic Details
Published inClinical orthopaedics and related research no. 260; p. 186
Main Authors Pinkowski, J L, Leeson, M C
Format Journal Article
LanguageEnglish
Published United States 01.11.1990
Subjects
Adult
Anaphylaxis - chemically induced
Chymopapain - adverse effects
Female
Humans
Intervertebral Disc Chemolysis
Skin Tests - adverse effects
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Summary:The allergic response to chymopapain intradiscal therapy has been well documented. The most serious of these reactions is anaphylactic shock, which may result in death. Various screening methods, including skin tests, have been proposed to identify susceptible patients. Anaphylactic shock occurred in a 40-year-old woman from application of the screening skin test. Appropriate therapeutic intervention should be readily accessible when this test is performed.
ISSN:0009-921X
DOI:10.1097/00003086-199011000-00030