Dioncopeltine A and dioncolactone A: Alkaloids from Triphyophyllum peltatum

The isolation of two novel alkaloids from Triphyophyllum peltatum is described. The complete stereostructure of dioncopeltine A, which is closely related to dioncophylline A, is established by spectroscopic, chiroptical, and degradative methods, and is furthermore confirmed by its transformation to...

Full description

Saved in:
Bibliographic Details
Published inPhytochemistry (Oxford) Vol. 30; no. 5; pp. 1691 - 1696
Main Authors Bringmann, Gerhard, Rübenacker, Martin, Vogt, Peter, Busse, Holger, Assi, Laurent Aké, Peters, Karl, von Schnering, Hans Georg
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 1991
Subjects
dioncolactone A
dioncopeltine A
Dioncophyllaceae
naphthylisoquinoline alkaloids
Triphyophyllum peltatum
Dioncophyllaceae
dioncopeltine A
naphthylisoquinoline alkaloids
Triphyophyllum peltatum
dioncolactone A
Online AccessGet full text

Cover

More Information
Summary:The isolation of two novel alkaloids from Triphyophyllum peltatum is described. The complete stereostructure of dioncopeltine A, which is closely related to dioncophylline A, is established by spectroscopic, chiroptical, and degradative methods, and is furthermore confirmed by its transformation to O-methyl-dioncopophylline A, as well as by X-ray crystallography. Dioncolactone A, which can be transformed into dioncopeltine A by reductive ring-opening, is the first naturally occurring representative of this novel type of ‘axially prostereogenic’ biaryl alkaloids.
ISSN:0031-9422
1873-3700
DOI:10.1016/0031-9422(91)84235-K