Concurrent cutaneous and hepatic hemangiomata in infancy: report of a case and a review of the literature

• Published in: The Journal of dermatologic surgery and oncology Vol. 4; no. 11; p. 869
• Main Authors: Berman, B, Lim, H
• Format: Journal Article
• Language: English
• Published: United States 01.11.1978
• Subjects: Digoxin - therapeutic use; Female; Heart Failure - drug therapy; Hemangioma - congenital; Hemangioma - therapy; Humans; Infant; Infant, Newborn; Liver Neoplasms - congenital; Liver Neoplasms - therapy; Neoplasms, Multiple Primary - congenital; Neoplasms, Multiple Primary - therapy; Prednisone - therapeutic use; Prognosis; Skin Neoplasms - congenital; Skin Neoplasms - therapy
• ISSN: 0148-0812
• DOI: 10.1111/j.1524-4725.1978.tb00569.x

Fifty-eight cases of concurrent cutaneous and hepatic hemangiomatosis in infants have been reported in the world literature. A fifty-ninth case is herewith reported and the literature is reviewed. Untreated cases have a mortality rate of 81%, whereas the mortality of treated cases is 29%. The main cause of death appears to be the consequence of arteriovenous shunting in the liver. Early and aggressive treatment by prednisone, radiotherapy to the liver, partial resection of liver, and ligation of the hepatic artery, each alone or in combinations, have been effective.