Chronic Kidney Disease: Mitochondrial Damage‐Induced Innate Immune Activation in Vascular Smooth Muscle Cells Promotes Chronic Kidney Disease‐Associated Plaque Vulnerability (Adv. Sci. 5/2021)

Like the old Chinese saying that a solid dyke can collapse because of the presence of an ant hole, the “ants” uremic toxins make the “solid” fibrous cap of atherosclerotic plaques susceptible to collapse via innate immune activation in vascular smooth muscle cells, as described by Ke Yang, Jinghong...

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Published inAdvanced science Vol. 8; no. 5
Main Authors Bi, Xianjin, Du, Changhong, Wang, Xinmiao, Wang, Xue‐Yue, Han, Wenhao, Wang, Yue, Qiao, Yu, Zhu, Yingguo, Ran, Li, Liu, Yong, Xiong, Jiachuan, Huang, Yinghui, Liu, Mingying, Liu, Chi, Zeng, Chunyu, Wang, Junping, Yang, Ke, Zhao, Jinghong
Format Journal Article
LanguageEnglish
Published Weinheim John Wiley & Sons, Inc 01.03.2021
John Wiley and Sons Inc
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Summary:Like the old Chinese saying that a solid dyke can collapse because of the presence of an ant hole, the “ants” uremic toxins make the “solid” fibrous cap of atherosclerotic plaques susceptible to collapse via innate immune activation in vascular smooth muscle cells, as described by Ke Yang, Jinghong Zhao, and co‐workers in article number 2002738.
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ISSN:2198-3844
2198-3844
DOI:10.1002/advs.202170026