Which Came First, the Frailty or the Heart Disease?

[...]they do not address the possibility of subclinical atherosclerosis or structural heart disease contributing to the development of pre-frailty and subsequent CVD. For now, it seems that the causal relationship between frailty and CVD remains as circular as the question of whether the chicken or...

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Bibliographic Details
Published inJournal of the American College of Cardiology Vol. 65; no. 10; pp. 984 - 986
Main Author Flint, Kelsey, MD
Format Journal Article
LanguageEnglish
Published New York Elsevier Limited 01.03.2015
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Summary:[...]they do not address the possibility of subclinical atherosclerosis or structural heart disease contributing to the development of pre-frailty and subsequent CVD. For now, it seems that the causal relationship between frailty and CVD remains as circular as the question of whether the chicken or the egg came first. [...]to advance the study of frailty and CVD to the next level, clinicians and researchers must meticulously study the mechanisms behind their link, and rigorously test treatments aimed at mitigating the adverse consequences associated with clinical and subclinical frailty and CVD.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2014.12.042