Immunohistochemical analysis of tissue remodelling during the anagen-catagen transition of the human hair follicle

• Published in: British journal of dermatology (1951) Vol. 137; no. 1; pp. 31 - 38
• Main Authors: COMMO, S., BERNARD, B.A.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.07.1997; Blackwell
• Subjects: Biological and medical sciences; Biomarkers - analysis; Cell Adhesion Molecules - analysis; Cell Adhesion Molecules - metabolism; Cytoskeletal Proteins - analysis; Cytoskeletal Proteins - metabolism; Dermatology; Desmogleins; Desmoplakins; Hair - growth & development; Hair - metabolism; Hair Follicle - growth & development; Hair Follicle - metabolism; Homeostasis; Humans; Immunohistochemistry; Intermediate Filament Proteins; Investigative techniques, diagnostic techniques (general aspects); Keratins - metabolism; Ki-67 Antigen - analysis; Ki-67 Antigen - metabolism; Medical sciences; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; Protein Precursors - analysis; Protein Precursors - metabolism; Transglutaminases - analysis; Transglutaminases - metabolism; Human; Immunohistochemistry; Pathology; catagen phase; Exploration; Hair follicle; Skin; anagen phase

Summary The transition from the growth phase (anagen) to the involution phase (catagen) involves profound morphological changes in the human hair follicle. Club hair and epithelial column formation, for example, are key features of the catagen phase, which result in the disruption of physical intera...