Exercise-induced fragmentation hemolysis : A simple in vivo test to evaluate heart valve hemolysis

Differentiating heart valve-related fragmentation hemolysis from other causes of hemolysis can occasionally be difficult, especially when findings on transthoracic or transesophageal echocardiography are minimal. We report a case in which the cause of hemolysis remained in doubt after thorough hemat...

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Bibliographic Details
Published inSouthern medical journal (Birmingham) Vol. 91; no. 10; pp. 970 - 972
Main Authors KAMPE, C. E, RODGERS, G. P, OSWALT, J. D, SANDBACH, J. F
Format Conference Proceeding Journal Article
LanguageEnglish
Published Hagerstown, MD Lippincott Williams & Wilkins 01.10.1998
Subjects
Anemia, Hemolytic - diagnosis
Anemia, Hemolytic - etiology
Biological and medical sciences
Cardiology. Vascular system
Endocardial and cardiac valvular diseases
Exercise Test
Heart
Humans
Male
Medical sciences
Middle Aged
Mitral Valve Insufficiency - surgery
Postoperative Complications
Predictive Value of Tests
Human
Mitral valve
Prosthesis
Cardiovascular disease
Hemopathy
Method
In vitro
Case study
Treatment
Hemolytic anemia
Cardiac valvular disease
Surgery
Complication
Diagnosis
Mitral valve disease
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Summary:Differentiating heart valve-related fragmentation hemolysis from other causes of hemolysis can occasionally be difficult, especially when findings on transthoracic or transesophageal echocardiography are minimal. We report a case in which the cause of hemolysis remained in doubt after thorough hematologic and cardiologic evaluations. The decision to reoperate on the valve was finally made, based on the result of exercise-induced increase in serum hemoglobin. Hemolytic anemia promptly resolved after reoperation. We believe this to be the first reported use of this in vivo test to support the diagnosis of valve-related hemolytic anemia.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:0038-4348
1541-8243
DOI:10.1097/00007611-199810000-00016