1-Benzyl-6,8-dimethyl-4-phenyl-2-tosyl-1,2,3,3a,4,6,7,8,9,9b-decahydropyrrolo[3,4- c ]pyrano[6,5- d ]pyrimidine-7,9-dione

• Published in: Acta crystallographica. Section E, Structure reports online Vol. 65; no. 11; pp. o2907 - o2908
• Main Authors: Chinnakali, K., Sudha, D., Jayagobi, M., Raghunathan, R., Fun, Hoong-Kun
• Format: Journal Article
• Language: English
• Published: International Union of Crystallography 01.11.2009
• ISSN: 1600-5368; 1600-5368
• DOI: 10.1107/S1600536809044341

The molecule of the title compound, C31H31N3O5S, adopts a folded conformation, with the sulfonyl-bound phenyl ring lying over the pyrimidine ring [dihedral angle = 12.04 (6)° and centroid–centroid separation = 3.6986 (8) Å]. The pyrrolidine ring adopts a twist conformation, the dihydropyran ring is in a half-chair conformation and the two rings are cis-fused. The tosyl group is attached to the pyrrolidine ring in an equatorial position while the benzyl group is axially attached. The molecular structure is stabilized by weak C—H...O hydrogen bonds and C—H...π interactions. In the crystal, pairs of molecules related by inversion symmetry are linked by C—H...O hydrogen bonds, forming chains propagating along the c axis which are cross-linked into a three-dimensional framework by further C—H...O links.