Cardiac output and ductal reopening during phototherapy in preterm infants

• Published in: Acta pædiatrica (Oslo) Vol. 88; no. 9; pp. 1014 - 1019
• Main Authors: BENDERS, M. J. N. L, VAN BEL, F, DE BOR, M. V
• Format: Journal Article
• Language: English
• Published: Oxford Blackwell 01.09.1999
• Subjects: Analysis of Variance; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Birth Weight; Blood Flow Velocity; Blood Pressure; Cardiac Output; Cardiac Output, Low - etiology; Ductus Arteriosus, Patent - etiology; Emergency and intensive care: neonates and children. Prematurity. Sudden death; Gestational Age; Heart Rate; Humans; Hyperbilirubinemia - therapy; Infant, Newborn; Infant, Premature; Intensive care medicine; Medical sciences; Phototherapy - adverse effects; Recurrence; Netherlands; Europe; Sonography; Human; Doppler ultrasound study; Iatrogenic; Respiratory disease; Persistent fetal circulation; Cardiovascular disease; Ductus arteriosus; Congenital disease; Blood flow; Phototherapy; Persistence; Newborn; Heart disease; Complication; Left ventricle performance; Comparative study; Left pulmonary artery
• ISSN: 0803-5253; 1651-2227
• DOI: 10.1080/08035259950168540

Left ventricular output (LVO), left pulmonary artery blood flow (LPA) and patency of the ductus arteriosus (PDA) were studied with 2D/pulsed Doppler ultrasound before, during and after phototherapy treatment in 27 preterm infants (gestational age < or =32 wk), who were exposed for a minimum of 12 h to phototherapy for non-haemolytic hyperbilirubinemia. In 14 infants (52%) the ductus arteriosus reopened during phototherapy, but ductal patency was not of haemodynamic importance. LVO initially decreased in preterm infants in whom the ductus did not reopen. From 12 h until discontinuation of phototherapy, LVO and LPA were higher than before phototherapy in all infants. After withdrawal of phototherapy, LVO and LPA returned to pre-phototherapy values.