A FACILE SYNTHESIS OF 3-GLYCOSYL-5-SUBSTITUTED-2-ISOXAZOLES

The 1,3-dipolar cycloaddition reaction between a 2-deoxy-D-aldose oxime (D-gluco or D-ribo) and an alkyne as dipolarophile (phenylacetylene, 2-propyn-1-ol, 3-chloro-1-propyne, or 3-bromo-1-propyne) is described. The new 3-glycosyl-5-substituted-2-isoxazoles are characterized physically and spectrosc...

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Bibliographic Details
Published inSynthetic communications Vol. 31; no. 12; pp. 1913 - 1920
Main Authors Fascio, Mirta L., D'Accorso, Norma B.
Format Journal Article
LanguageEnglish
Published PHILADELPHIA Taylor & Francis Group 01.01.2001
Taylor & Francis
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
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Summary:The 1,3-dipolar cycloaddition reaction between a 2-deoxy-D-aldose oxime (D-gluco or D-ribo) and an alkyne as dipolarophile (phenylacetylene, 2-propyn-1-ol, 3-chloro-1-propyne, or 3-bromo-1-propyne) is described. The new 3-glycosyl-5-substituted-2-isoxazoles are characterized physically and spectroscopically.
ISSN:0039-7911
1532-2432
DOI:10.1081/SCC-100104343