Metastatic disease in the cerebellum. The LSU experience in 1981-1993

We retrospectively determined the outcome of management of metastatic disease in the cerebellum (MDC) in 45 patients because MDC is considered to be more immediately life-threatening than metastases in other intracranial locations. Treatment consisted of tumor resection and radiotherapy (RR; n = 11)...

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Bibliographic Details
Published inAmerican journal of clinical oncology Vol. 19; no. 5; p. 509
Main Authors Ampil, F L, Nanda, A, Willis, B K, Nandy, I, Meehan, R
Format Journal Article
LanguageEnglish
Published United States 01.10.1996
Subjects
Aged
Cerebellar Neoplasms - mortality
Cerebellar Neoplasms - secondary
Cerebellar Neoplasms - therapy
Female
Humans
Male
Middle Aged
Prognosis
Retrospective Studies
Survival Rate
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Summary:We retrospectively determined the outcome of management of metastatic disease in the cerebellum (MDC) in 45 patients because MDC is considered to be more immediately life-threatening than metastases in other intracranial locations. Treatment consisted of tumor resection and radiotherapy (RR; n = 11) or of radiotherapy alone (RA; n = 34). Significant differences in the median survival (15 months for RR and 3 months for RA, p = 0.005) and in survival rates at 1 year (61 +/- 30% for RR and 9 +/- 10% for RA, p < 0.001) and at 2 years (15 +/- 22% for RR and 0% for RA, p < 0.05) were noted. This combined management program of surgery followed by radiotherapy for MDC produced a worthwhile gain in survival.
ISSN:0277-3732
DOI:10.1097/00000421-199610000-00016