Continuous venovenous hemofiltration with dialysis in combination with total hepatectomy and portocaval shunting. Bridge to liver transplantation

• Published in: Transplantation Vol. 62; no. 1; p. 130
• Main Authors: Hammer, G B, So, S K, Al-Uzri, A, Conley, S B, Concepcion, W, Cox, K L, Berquist, W E, Esquivel, C O
• Format: Journal Article
• Language: English
• Published: United States 15.07.1996
• Subjects: Child, Preschool; Dialysis; Hemofiltration; Hepatectomy; Humans; Liver Failure, Acute - surgery; Liver Transplantation - methods; Male; Portacaval Shunt, Surgical
• ISSN: 0041-1337
• DOI: 10.1097/00007890-199607150-00026

Children who experience acute liver failure following liver transplantation will have multiple organ failure and a high rate of mortality unless emergency retransplantation can be performed. Transplant hepatectomy with portocaval shunting has been described as a bridge to transplantation in the most severe cases, as well as in patients with fulminant hepatic failure at high risk for mortality who have not undergone liver transplantation. Patients with multiple organ failure who have undergone hepatectomy require renal replacement therapy. Continuous hemofiltration may be used in patients with fulminant hepatic failure to facilitate fluid removal and circulatory and metabolic balance. We used continuous venovenous hemofiltration with dialysis following hepatectomy with portocaval shunting in a patient who remained anhepatic for 66 hr in order to achieve circulatory and metabolic homeostasis as well as stable neurologic function prior to successful retransplantation.