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Many microorganisms form multicellular structures that are critical for basic biological functions. Biofilms, formed by the adherence of many bacterial cells to a surface, are a classic example of one such structure. But classifying these structures and their development is a major challenge for res...

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Bibliographic Details
Published inBioTechniques Vol. 56; no. 1; p. 9
Main Authors Blow, Nathan, Lo, Patrick C. H
Format Journal Article
LanguageEnglish
Published Future Science Ltd 01.01.2014
Taylor & Francis Group
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Summary:Many microorganisms form multicellular structures that are critical for basic biological functions. Biofilms, formed by the adherence of many bacterial cells to a surface, are a classic example of one such structure. But classifying these structures and their development is a major challenge for researchers interested in studying biofilms and other multicellular formations. While visual inspection by a trained scientist can be used to provide a qualitative measure of phenotype, robust arrays of quantitative measurements that could be used to accurately differentiate complex microbial structures are more difficult to obtain. In this issue of BioTechniques, Aimee Dudley and her colleagues introduce a new automated imaging and quantitative analysis platform that can be used to study the genetic and molecular pathways responsible for different colony morphologies in yeast.
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ISSN:0736-6205
1940-9818
DOI:10.2144/000114118