CARDIOPROTECTION BY STIMULATION OF MITOCHONDRIAL BENZODIAZEPINE RECEPTORS DURING REPERFUSION, IN A PORCINE ACUTE ISCHEMIA-REPERFUSION MODEL

Conclusion In a preclinical model of acute myocardial infarction, intracoronary administration of 4ClD just before the onset of reperfusion reduces microvascular damage and leads to faster ST resolution without any adverse haemodynamic complications; a smaller in magnitude, not statistically signifi...

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Published inJournal of the American College of Cardiology Vol. 59; no. 13; p. E545
Main Authors Terrovitis, John, Katsaros, Lampros, Tsamatsoulis, Michalis, Sventzouri, Stefania, Sousonis, Vassilios, Bonios, Michalis, Kapelios, Christos, Vakrou, Styliani, Ntalianis, Argyrios, Papalois, Apostolos, O'Rourke, Brian, Nanas, John
Format Journal Article
LanguageEnglish
Published New York Elsevier Inc 27.03.2012
Elsevier Limited
Subjects
Cardiology
Cardiovascular
Heart attacks
Internal Medicine
Ischemia
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Summary:Conclusion In a preclinical model of acute myocardial infarction, intracoronary administration of 4ClD just before the onset of reperfusion reduces microvascular damage and leads to faster ST resolution without any adverse haemodynamic complications; a smaller in magnitude, not statistically significant, reduction in infarct size was also found.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(12)60546-4