Use of stem cells in bone regeneration in cleft palate patients: review and recommendations

This study was conducted to review the efficacy of different sources of stem cells in bone regeneration of cleft palate patients. The majority of previous studies focused on the transplantation of bone marrow mesenchymal stem cells. However, other sources of stem cells have also gained considerable...

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Bibliographic Details
Published inJournal of the Korean Association of Oral and Maxillofacial Surgeons Vol. 48; no. 2; pp. 71 - 78
Main Authors Amiri, Mohammad Amin, Lavaee, Fatemeh, Danesteh, Hossein
Format Journal Article
LanguageEnglish
Published Korea (South) The Korean Association of Oral and Maxillofacial Surgeons 30.04.2022
대한구강악안면외과학회
Subjects
Review
치의학
Cleft palate
Craniofacial abnormalities
Bone regeneration
Tissue engineering
Stem cells
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Summary:This study was conducted to review the efficacy of different sources of stem cells in bone regeneration of cleft palate patients. The majority of previous studies focused on the transplantation of bone marrow mesenchymal stem cells. However, other sources of stem cells have also gained considerable attention, and dental stem cells have shown especially favorable outcomes. Additionally, approaches that apply the co-culture and co-transplantation of stem cells have shown promising results. The use of different types of stem cells, based on their accessibility and efficacy in bone regeneration, is a promising method in cleft palate bone regeneration. In this regard, dental stem cells may be an ideal choice due to their efficacy and accessibility. In conclusion, stem cells, despite the lengthy procedures required for culture and preparation, are a suitable alternative to conventional bone grafting techniques.
Bibliography:ObjectType-Article-2
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ISSN:2234-7550
2234-5930
DOI:10.5125/jkaoms.2022.48.2.71