Evaluation of Antibiotic Prescribing in a Veterans Affairs Outpatient Setting: Identification of Stewardship Targets

• Published in: The Senior care pharmacist Vol. 34; no. 4; p. 268
• Main Authors: Clark, Collin M, White, Alexis T, Sellick, Jr, John A, Mergenhagen, Kari A
• Format: Journal Article
• Language: English
• Published: United States 01.04.2019
• ISSN: 2639-9636; 2639-9644
• DOI: 10.4140/TCP.n.2019.268

To evaluate antibiotic prescribing practices for geriatric outpatients in a Veterans Affairs (VA) health care system. This is a single-center, observational, prospective cohort study. Veterans Affairs Healthcare System. Outpatients treated with oral antibiotics between June and September 2017. None. Appropriate therapy was assessed based on clinical practice guidelines. Multivariable logistic regression was used to identify predictors of appropriate treatment. This study yielded 1,063 prescriptions for analysis. No significant difference was observed for antibiotic indicated (60%), correct drug (50%), or correct duration (75%). Patients older than 65 years of age were more likely to receive an inappropriate dose (86% vs. 76%; < 0.002). In the multivariable analysis, patients with chronic obstructive pulmonary disease (COPD) were more than 1.4 times likely to be treated appropriately (95% confidence interval 1.03-1.9) versus those without COPD. Older patients were not more likely to be re-treated or admitted within 30 days. Antibiotics are often inappropriately used in the outpatient setting; but not more frequently in elderly patients. Older adults were more likely to be prescribed an antibiotic at an inappropriate dose. Opportunities exist for stewardship teams to provide value in the outpatient setting to ensure appropriate antibiotic prescribing with a focus on dosing.