The Effect of Antioxidant Agents on Cisplatin-Induced Laryngeal Histological Alterations in Rats

• Published in: Journal of medicinal food Vol. 24; no. 2; p. 197
• Main Authors: Başak, Kayhan, Demir, Mehmet Gökhan, Altıntoprak, Niyazi, Aydın, Sedat
• Format: Journal Article
• Language: English
• Published: United States 01.02.2021
• Subjects: Animals; Antioxidants - pharmacology; Antioxidants - therapeutic use; Cisplatin; Laryngeal Diseases - chemically induced; Laryngeal Diseases - drug therapy; Larynx - drug effects; Oxidative Stress - drug effects; Rats; Rats, Wistar; larynx; mucositis; histological alterations; cisplatin; antioxidants

The larynx-related adverse effects that depend on cisplatin decrease patient comfort and many antioxidants have been used to eliminate these side effects. We aimed to identify the laryngeal mucosal changes imposed by cisplatin and investigated whether antioxidants, and their healing effects on these...