A case control study of necrotizing enterocolitis occurring over 8 years in a neonatal intensive care unit

The perinatal histories of 27 newborn infants with NEC were compared to those of 54 infants of equivalent birth weight who did not have NEC during an 8-year study period to see if possible predisposing factors were independent of the confounding effect of birth weight. No differences were observed i...

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Bibliographic Details
Published inEuropean journal of pediatrics Vol. 146; no. 4; p. 398
Main Authors De Curtis, M, Paone, C, Vetrano, G, Romano, G, Paludetto, R, Ciccimarra, F
Format Journal Article
LanguageEnglish
Published Germany 01.07.1987
Subjects
Birth Weight
Enterocolitis, Pseudomembranous - etiology
Female
Fetal Growth Retardation - complications
Fetal Membranes, Premature Rupture - complications
Gestational Age
Humans
Infant, Newborn
Infant, Premature, Diseases - etiology
Intensive Care Units, Neonatal
Male
Pregnancy
Risk Factors
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Summary:The perinatal histories of 27 newborn infants with NEC were compared to those of 54 infants of equivalent birth weight who did not have NEC during an 8-year study period to see if possible predisposing factors were independent of the confounding effect of birth weight. No differences were observed in gestational age, degree of intrauterine growth retardation, premature rupture of membranes, perinatal asphyxia, skin temperature at admission, haematocrit, presence or absence of respiratory distress syndrome, umbilical catheter placement, start and type of feeding or presence of positive blood cultures. Prematurity is the greatest risk factor predisposing to the development of NEC and the perinatal problems which precede the onset of NEC are common among all premature infants.
ISSN:0340-6199
DOI:10.1007/BF00444947