EFFICACY OF TYPE 1 BOVINE COLLAGEN PARTICLES IN THE TOPICAL MANAGEMENT OF DIABETIC FOOT ULCER

• Published in: Journal of evolution of medical and dental sciences Vol. 5; no. 67; pp. 4769 - 4773
• Main Authors: Kshirsagar, Ashok Y, Pandey, Yash, Baur, Sourav, Deka, Hrishikesh, Verma, Amit, Kesarwani, Abhinav, Bhagat, Abhishek, Surushe, Aniket
• Format: Journal Article
• Language: English
• Published: Akshantala Enterprises Private Limited 22.08.2016
• Subjects: Collagen; Diabetic foot; Health aspects
• ISSN: 2278-4748; 2278-4802
• DOI: 10.14260/jemds/2016/1087

Diabetic foot ulcer will lead to a significant prolonged stress to the patients. Biological dressings like type 1 bovine collagen particles has advantage over conventional dressing in terms of early healing of wound. A total of 100 patients suffering from ulcer were taken randomly for this study after explaining the procedure and purpose of study. This was a comparative study between conventional dressing of ulcer and dressing with type 1 bovine collagen particles. There was significant difference in the result of collagen granules and conventional dressing. Collagen granules had better healing response rate. AIMS AND OBJECTIVES. To study the efficacy of topical agent type 1 bovine collagen granules in the management of diabetic foot ulcers. METHODOLOGY The patients who were admitted for diabetic foot ulcer at Dept. of Surgery, KIMS, Karad, tertiary care teaching centre during the study period were screened. 50 patients in the test group were treated with topical dressings of collagen granules. The control group of 50 patients was treated with conventional topical dressings and bedside debridement. Ulcer was noted using visual score. RESULTS The reduction of slough is as early as 3rd week in test group than the control group. The number of patients with 75- 100% wound filled with granulation tissue is as early as 3rd week in test group than the control group where it took more than 4 weeks. The number of patients who underwent secondary suturing, skin grafting, and flap are significantly higher and also as early as 3 rd week in test group than the control group. CONCLUSION Collagen granules topical application enhanced wound healing of diabetic foot ulcer as compared to conventional treatment modalities. KEYWORDS Collagen Particles, Granulation Tissue, Wound.