Cell division, chromosomal aberration, and micronuclei formation in human peripheral blood lymphocytes. Effect of stannic chloride on donor's age

• Published in: Biological trace element research Vol. 38; no. 1; p. 55
• Main Author: Ganguly, B B
• Format: Journal Article
• Language: English
• Published: United States 01.07.1993
• Subjects: Adolescent; Adult; Age Factors; Aged; Cell Division - drug effects; Child; Chromosome Aberrations; Female; Humans; In Vitro Techniques; Lymphocytes - drug effects; Lymphocytes - ultrastructure; Male; Micronucleus Tests; Middle Aged; Mitotic Index - drug effects; Tin Compounds - toxicity

Age related cytotoxicity of stannic chloride was evaluated in human lymphocytes considering mitotic index (MI), damaged cell (DC), chromosome aberration (CA), and micronuclei formation (MNC) as endpoints. Significant elevation of DCs, CAs, MNCs, and reduction of MI were observed in all classified ag...