Cell division, chromosomal aberration, and micronuclei formation in human peripheral blood lymphocytes. Effect of stannic chloride on donor's age

Age related cytotoxicity of stannic chloride was evaluated in human lymphocytes considering mitotic index (MI), damaged cell (DC), chromosome aberration (CA), and micronuclei formation (MNC) as endpoints. Significant elevation of DCs, CAs, MNCs, and reduction of MI were observed in all classified ag...

Full description

Saved in:
Bibliographic Details
Published inBiological trace element research Vol. 38; no. 1; p. 55
Main Author Ganguly, B B
Format Journal Article
LanguageEnglish
Published United States 01.07.1993
Subjects
Adolescent
Adult
Age Factors
Aged
Cell Division - drug effects
Child
Chromosome Aberrations
Female
Humans
In Vitro Techniques
Lymphocytes - drug effects
Lymphocytes - ultrastructure
Male
Micronucleus Tests
Middle Aged
Mitotic Index - drug effects
Tin Compounds - toxicity
Online AccessGet more information
ISSN0163-4984
DOI10.1007/BF02783982

Cover

Abstract Age related cytotoxicity of stannic chloride was evaluated in human lymphocytes considering mitotic index (MI), damaged cell (DC), chromosome aberration (CA), and micronuclei formation (MNC) as endpoints. Significant elevation of DCs, CAs, MNCs, and reduction of MI were observed in all classified age groups compared to each control set. The mean frequencies of abnormalities show a statistically significant increase with subject's age. Linearity of the effect of age was common for both untreated and treated lymphocytes of both sexes.
AbstractList Age related cytotoxicity of stannic chloride was evaluated in human lymphocytes considering mitotic index (MI), damaged cell (DC), chromosome aberration (CA), and micronuclei formation (MNC) as endpoints. Significant elevation of DCs, CAs, MNCs, and reduction of MI were observed in all classified age groups compared to each control set. The mean frequencies of abnormalities show a statistically significant increase with subject's age. Linearity of the effect of age was common for both untreated and treated lymphocytes of both sexes.
Author Ganguly, B B
Author_xml – sequence: 1
  givenname: B B
  surname: Ganguly
  fullname: Ganguly, B B
  organization: Biochemistry Unit, Indian Statistical Institute, Calcutta
BackLink https://www.ncbi.nlm.nih.gov/pubmed/7691132$$D View this record in MEDLINE/PubMed
BookMark eNotkEtLAzEcxHOo1LZ68S7k5sWtSfaRzVFLq0LBi57Lf_NwI3ksyVbox_Abt9SeBmaY38DM0STEoBG6o2RJCeFPLxvCeFuKlk3QjNCmLCrRVtdonvMPIZQzUU7RlDeC0pLN0N9KO4eV_bXZxvCIZZ-ijzl6cBg6nRKMZx-Cwt7KFMNeOm2xicmfI2wD7vceAh50skOv06nZuRgVdgc_9FEeRp2XeG2MliOOBucRQrDyNOViskrjE0TFENNDxvCtb9CVAZf17UUX6Guz_ly9FduP1_fV87aQrGVjIau6FhyglcCpUFywulOsUwo4SM6ZItxUJa1BGa65qWvO6kY3BsBwQlvBFuj-nzvsO6_VbkjWQzrsLtewIyYWaCM
CitedBy_id crossref_primary_10_2903_j_efsa_2018_5295
crossref_primary_10_3109_01480545_2013_838773
crossref_primary_10_1007_s11356_019_04439_0
crossref_primary_10_1007_s13237_019_00300_4
crossref_primary_10_1016_0921_8734_95_90001_2
crossref_primary_10_1016_j_mrfmmm_2018_03_005
crossref_primary_10_1590_S0102_311X1998000700011
crossref_primary_10_1016_j_mrgentox_2017_10_004
crossref_primary_10_1016_0165_1161_94_90003_5
ContentType Journal Article
DBID CGR
CUY
CVF
ECM
EIF
NPM
DOI 10.1007/BF02783982
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
DatabaseTitleList MEDLINE
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod no_fulltext_linktorsrc
Discipline Anatomy & Physiology
ExternalDocumentID 7691132
Genre Research Support, Non-U.S. Gov't
Journal Article
GroupedDBID ---
-Y2
-~X
.86
.GJ
.VR
06C
06D
0R~
0VY
199
1N0
2.D
203
23N
28-
29~
2J2
2JN
2JY
2KG
2KM
2LR
2VQ
2~H
30V
3SX
4.4
406
408
40D
40E
4P2
53G
5GY
5VS
67N
6NX
78A
7X7
88E
88I
8AO
8CJ
8FE
8FH
8FI
8FJ
8TC
8UJ
95-
95.
95~
96X
A8Z
AAAVM
AABHQ
AACDK
AAHBH
AAHNG
AAIAL
AAJBT
AAJKR
AANXM
AANZL
AAPKM
AARHV
AARTL
AASML
AATNV
AATVU
AAUYE
AAWCG
AAYIU
AAYQN
AAYTO
AAYZH
ABAKF
ABBRH
ABDBE
ABDZT
ABECU
ABFSG
ABFTV
ABHLI
ABHQN
ABJNI
ABJOX
ABKCH
ABMNI
ABMQK
ABNWP
ABOCM
ABPLI
ABQBU
ABQSL
ABRTQ
ABSXP
ABTEG
ABTHY
ABTKH
ABTMW
ABUWG
ABWNU
ABXPI
ACAOD
ACBXY
ACCUX
ACDTI
ACGFS
ACGOD
ACHSB
ACHXU
ACKNC
ACMDZ
ACMLO
ACOKC
ACOMO
ACPIV
ACPRK
ACSNA
ACSTC
ACZOJ
ADBBV
ADHHG
ADHIR
ADHKG
ADKNI
ADKPE
ADNWM
ADRFC
ADTPH
ADURQ
ADYFF
ADYPR
ADZKW
AEBTG
AEFQL
AEGAL
AEGNC
AEJHL
AEJRE
AEKMD
AEMSY
AENEX
AEOHA
AEPYU
AESKC
AETLH
AEUYN
AEVLU
AEXYK
AEZWR
AFBBN
AFDZB
AFEXP
AFGCZ
AFHIU
AFKRA
AFLOW
AFOHR
AFQWF
AFRAH
AFWTZ
AFZKB
AGAYW
AGDGC
AGGDS
AGJBK
AGMZJ
AGQEE
AGQMX
AGQPQ
AGRTI
AGWIL
AGWZB
AGYKE
AHAVH
AHBYD
AHKAY
AHMBA
AHPBZ
AHSBF
AHWEU
AIAKS
AIGIU
AIIXL
AILAN
AITGF
AIXLP
AJBLW
AJRNO
AJZVZ
AKMHD
ALIPV
ALMA_UNASSIGNED_HOLDINGS
ALWAN
AMKLP
AMXSW
AMYLF
AMYQR
AOCGG
ARMRJ
ASPBG
ATHPR
AVWKF
AXYYD
AYFIA
AZFZN
AZQEC
B-.
BA0
BBNVY
BBWZM
BDATZ
BENPR
BGNMA
BHPHI
BKSAR
BPHCQ
BSONS
BVXVI
CAG
CCPQU
CGR
COF
CS3
CSCUP
CUY
CVF
D1J
DDRTE
DNIVK
DPUIP
DU5
DWQXO
EBD
EBLON
EBS
ECM
EIF
EIOEI
EJD
EMOBN
ESBYG
F5P
FEDTE
FERAY
FFXSO
FIGPU
FINBP
FNLPD
FRRFC
FSGXE
FWDCC
FYUFA
G-Y
G-Z
GGCAI
GGRSB
GJIRD
GNUQQ
GNWQR
GQ7
H13
HCIFZ
HF~
HG6
HMCUK
HMJXF
HRMNR
HVGLF
HZ~
IJ-
IKXTQ
ITM
IWAJR
I~X
I~Z
J-C
J0Z
JBSCW
JZLTJ
KOV
LK8
LLZTM
M1P
M2P
M4Y
M7P
MA-
N2Q
NB0
NDZJH
NF0
NPM
NPVJJ
NQJWS
NU0
O9-
O93
O9G
O9I
O9J
OVD
P19
PCBAR
PF0
PHGZM
PHGZT
PJZUB
PPXIY
PQGLB
PQQKQ
PROAC
PSQYO
PT4
PT5
Q2X
QOK
QOR
QOS
R4E
R89
R9I
RHV
RNI
RNS
ROL
RPX
RSV
RZK
S16
S1Z
S26
S27
S28
S3A
S3B
SAP
SBL
SBY
SCLPG
SDH
SDM
SHX
SISQX
SJYHP
SNE
SNPRN
SNX
SOHCF
SOJ
SPISZ
SRMVM
SSLCW
SSXJD
STPWE
SV3
SZN
T13
T16
TEORI
TSG
TUC
U2A
U9L
UG4
UKHRP
UOJIU
UTJUX
UZXMN
VC2
VFIZW
W48
WK6
WK8
YLTOR
YZZ
ZGI
ZMTXR
ZOVNA
~02
~A9
~EX
~KM
ID FETCH-LOGICAL-c282t-c45597aa8ca719d7925bd2bdda7ac772d07f4315adf7e7f557256e6faaf701892
ISSN 0163-4984
IngestDate Tue Aug 05 11:35:00 EDT 2025
IsPeerReviewed true
IsScholarly true
Issue 1
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c282t-c45597aa8ca719d7925bd2bdda7ac772d07f4315adf7e7f557256e6faaf701892
PMID 7691132
ParticipantIDs pubmed_primary_7691132
PublicationCentury 1900
PublicationDate 1993-Jul
PublicationDateYYYYMMDD 1993-07-01
PublicationDate_xml – month: 07
  year: 1993
  text: 1993-Jul
PublicationDecade 1990
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Biological trace element research
PublicationTitleAlternate Biol Trace Elem Res
PublicationYear 1993
References 3631081 - Am J Hum Genet. 1987 Sep;41(3):484-92
2807302 - Hum Toxicol. 1989 Sep;8(5):349-53
689896 - Hereditas. 1978;88(2):263-7
2392127 - Mutat Res. 1990 Sep;245(1):33-9
4010696 - Mutat Res. 1985 Jul;143(3):155-60
2051786 - Mech Ageing Dev. 1991 Feb;57(2):125-37
3960044 - Mutat Res. 1986 Apr-May;170(1-2):55-74
6627503 - Chem Biol Interact. 1983 Sep 1;46(2):189-200
3251679 - Cytobios. 1988;56(224):23-7
312662 - Biochim Biophys Acta. 1979 Apr 26;562(2):240-51
1377352 - Mutat Res. 1992 Jun;282(2):61-7
6493251 - Mutat Res. 1984 Oct;129(1):77-88
3520305 - Mutat Res. 1986 Jun;170(3):151-60
2733711 - Mutat Res. 1989 Jun;212(2):149-54
References_xml – reference: 312662 - Biochim Biophys Acta. 1979 Apr 26;562(2):240-51
– reference: 2807302 - Hum Toxicol. 1989 Sep;8(5):349-53
– reference: 3960044 - Mutat Res. 1986 Apr-May;170(1-2):55-74
– reference: 1377352 - Mutat Res. 1992 Jun;282(2):61-7
– reference: 4010696 - Mutat Res. 1985 Jul;143(3):155-60
– reference: 2733711 - Mutat Res. 1989 Jun;212(2):149-54
– reference: 689896 - Hereditas. 1978;88(2):263-7
– reference: 2051786 - Mech Ageing Dev. 1991 Feb;57(2):125-37
– reference: 2392127 - Mutat Res. 1990 Sep;245(1):33-9
– reference: 6627503 - Chem Biol Interact. 1983 Sep 1;46(2):189-200
– reference: 6493251 - Mutat Res. 1984 Oct;129(1):77-88
– reference: 3631081 - Am J Hum Genet. 1987 Sep;41(3):484-92
– reference: 3520305 - Mutat Res. 1986 Jun;170(3):151-60
– reference: 3251679 - Cytobios. 1988;56(224):23-7
SSID ssj0017293
Score 1.4307648
Snippet Age related cytotoxicity of stannic chloride was evaluated in human lymphocytes considering mitotic index (MI), damaged cell (DC), chromosome aberration (CA),...
SourceID pubmed
SourceType Index Database
StartPage 55
SubjectTerms Adolescent
Adult
Age Factors
Aged
Cell Division - drug effects
Child
Chromosome Aberrations
Female
Humans
In Vitro Techniques
Lymphocytes - drug effects
Lymphocytes - ultrastructure
Male
Micronucleus Tests
Middle Aged
Mitotic Index - drug effects
Tin Compounds - toxicity
Title Cell division, chromosomal aberration, and micronuclei formation in human peripheral blood lymphocytes. Effect of stannic chloride on donor's age
URI https://www.ncbi.nlm.nih.gov/pubmed/7691132
Volume 38
hasFullText
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1NSxxBEG3WiOAlRI2YL6mDJId1ZHenZ3rmKJIogp4UvEl_ouDOLDo5bP5F_nGquntmxy-MXoZlGprdfm-bqurXrxjbURPDpeIm0dJqTFBGKinTUifaKpkV1nHpbRdPTvOjc358kV0MBrOeaul3o_b0nyfvlbwFVXyHuNIt2Vcg202KL_Az4otPRBif_4XxARXe6EIVlbxosfQVqevu6ik5ACh7G-BtFZpTEt9VZGB8vbi0SAWP0KiPPI-9ycBNkLMPb-YIda3nGI3uDaPNMcaWFE9S2xx9Reo9Y-m8wdRVrP3L--Ki0OvSM6G5lbiJ2KBXH0aXoa4afUiF09j2OraCNvF2XtoJV7v6ZJ4mvAxd39oNNi0eESnslsGg99EmPmql6dQFpAy9iXpozqYeTpHjPp2-PPjATjuOLLElzCuoUSpVd-KpEyYaafCCDz_ivp1t_DarbCXO8SAT8RHJ2Qf2PqYSsB94scYGtlpnG_uVbOrpHL6DF_f6U5MN9peoAi1VdqFHFFgQZReQJtCjCXQ0gesKPE1gQRPwNIE-TSDQBGoHkSbQ0gRwEk-TH3eAsHxk579-nh0cJbEbR6IxLW8SzSn5lLLQUoxLI8pJpsxEGSOF1LiWZiQcRqOZNE5Y4bJMYDRtcyelE6NxUU422buqruwWA6XGuTL-lHnMHcelFs5wU5CZHvlffmKbYWEvZ8Fy5TKu-OfnBr6w1QUdv7Jlh_9w-w3DxUZte4z_AZrlb_g
linkProvider National Library of Medicine
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Cell+division%2C+chromosomal+aberration%2C+and+micronuclei+formation+in+human+peripheral+blood+lymphocytes.+Effect+of+stannic+chloride+on+donor%27s+age&rft.jtitle=Biological+trace+element+research&rft.au=Ganguly%2C+B+B&rft.date=1993-07-01&rft.issn=0163-4984&rft.volume=38&rft.issue=1&rft.spage=55&rft_id=info:doi/10.1007%2FBF02783982&rft_id=info%3Apmid%2F7691132&rft_id=info%3Apmid%2F7691132&rft.externalDocID=7691132
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0163-4984&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0163-4984&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0163-4984&client=summon