PREVALENCE OF ESBL PRODUCERS IN FAMILY ENTEROBACTERIACEAE ISOLATED FROM D. Y. PATIL MEDICAL COLLEGE & HOSPITAL, KOLHAPUR

Extended Spectrum Beta Lactamases (ESBL) producing Gram Negative Bacilli (GNB) is a worldwide problem. Although few studies have reported on the prevalence of ESBL producers in Indian hospitals, ESBL producing bacteria may have evolved in several hospitals all over the country. Therefore the study w...

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Bibliographic Details
Published inJournal of evolution of medical and dental sciences Vol. 4; no. 70; pp. 12241 - 12245
Main Authors Vatkar, V.S, Shadija, P.G, Ghosh, S.J
Format Journal Article
LanguageEnglish
Published Akshantala Enterprises Private Limited 31.08.2015
Subjects
Beta lactamases
Drug resistance
Medical colleges
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Summary:Extended Spectrum Beta Lactamases (ESBL) producing Gram Negative Bacilli (GNB) is a worldwide problem. Although few studies have reported on the prevalence of ESBL producers in Indian hospitals, ESBL producing bacteria may have evolved in several hospitals all over the country. Therefore the study was carried out at Dept. of Microbiology, D. Y. Patil Hospital & Research Center, Kadamwadi, Kolhapur, to examine the incidence of ESBL producing strains & multiple drug resistance in GNB during the period of Dec. 2009 to May 2011. A total number of 197 isolates belonging to family Enterobacteriaceae were isolated from various clinical samples & studied for ESBL production by Kirby- Bauer disc diffusion test as per CLSI (Clinical Laboratory Standards Institute) standards & confirmed by using DDST (Double Disc Synergy Test) & MIC. Out of 197 isolates, 83 isolates (42.13%) were potential ESBL producers on the basis of resistance or decreased sensitivity to third generation Cephalosporins (3GC). ESBL production is detected by Jarlier DDST for these 83 isolates. Seventy (35.53%) isolates out of these 83 isolates were DDST positive. All the ESBL producers were tested for MIC and antibiotic sensitivity test (AST). KEYWORDS: Extended Spectrum beta Lactamases, 3GC resistance, Enterobacteriaceae.
ISSN:2278-4748
2278-4802
DOI:10.14260/jemds/2015/1764