Septic shock in patients admitted to intensive care unit with COVID-19 pneumonia

• Published in: Eurasian journal of pulmonology Vol. 23; no. 2; p. 95
• Main Authors: Rollas, Kazim, Ersan, Gursel, Zincircioglu, Ciler, Sahar, Isa, Caliskan, Taner, Kose, Isil Guldogan, Saritas, Aykut, Uzun, Ugur, Senoglu, Nimet
• Format: Journal Article
• Language: English
• Published: AVES 01.05.2021
• Subjects: Bacterial pneumonia; China; Coronaviruses; Health aspects; Mortality; Pneumonia; Septic shock; China
• ISSN: 2148-3620
• DOI: 10.4103/ejop.ejop_101_20

BACKGROUND: The aim of this study was to determine mortality rates and to evaluate clinical features of coronavirus disease 2019 (COVID-19) patients with septic shock in intensive care unit (ICU). MATERIALS AND METHODS: The medical records of COVID-19 patients requiring ICU admission were retrospectively reviewed over a 3-month period. RESULTS: Forty patients with COVID-19 admitted to the ICU were screened. Two patients died within 24 h after ICU admission. After these patients were excluded, septic shock was detected in 11 (28%) of 38 patients during the 30-day follow-up period. Ten (91%) of the 11 patients with septic shock died in the ICU. Eight (72%) of the 11 patients had nosocomial infection during 30-day follow-up period. Six (54%) of 11 septic shock patients had positive culture results for bacterial pneumonia on the day of septic shock. The median time from symptom onset to septic shock was 14 (5-34) days. The median duration from ICU admission until septic shock was 8 (1-28) days. All of the patients with septic shock underwent invasive mechanical ventilation (IMV). CONCLUSION: COVID-19 patients with septic shock have higher mortality rates, percentage of nosocomial infection, and IMV requirement. Keywords: Acute disease, COVID-19, critical illness, intensive care, septic shock